Category: FAQ

How are steroids used in medicine?

Anabolic steroids (AAS) were created to combat various ailments. People have already forgotten what the purpose of the AAS is and are concerned that they are used in sports everywhere, even chess players … But it is worth remembering what they were made of. In medicine, they are used to treat:

  • Burns;
  • Injuries of a different nature;
  • Immunodeficiency;
  • Testosterone deficiency in men (HRT);
  • To strengthen bones;
  • For the prevention of stunted growth in children;
  • Osteoporosis;
  • Arthritis;
  • Arthrosis;
  • Osteochondrosis;
  • Impotence;
  • Male menopause;
  • Infertility;
  • Oligospermia;
  • Mammary cancer.

1. HRT (hormone replacement therapy) is a condition characterized by low testosterone levels in men, for its treatment, “testosterone enanthate” or “propionate” is prescribed. This is a vital measure, because testosterone is the main hormone in the body of a man, and its decline leads to a slow wilt and weakening of the body. It is very important to maintain the physiological norms of the hormone for normal well-being and health.

2. Methandrostenolone. In treating burns, methandrostenolone is used, but its use does not end there. It is also used in the treatment of alcoholic hepatitis, diseases associated with diabetes, for injuries of various origins, degeneration, as well as for diseases when protein synthesis is difficult. As you can see, the range of application is very wide.

Human growth hormone (somatotropin) is a universal hormone and affects the cells in the body. GH is also used in all the cases mentioned above. Its main use in pediatric medicine is for growth retardation. It directly affects the height of the body at an early age. On an adult, he has no such effect. In adults, the pituitary growth zones close during maturation – this is when the bones stop growing in length.

3. Testosterone and its derivatives are, as a rule, highly androgens. It has the ability to convert to estrogen (female sex hormones). They appear in the body of a man precisely because of aromatase. In the female body, they are produced by the hatchmen. Therefore, in certain diseases such as (gynecomastia, or breast cancer), do not prescribe drugs capable of converting into estrogen. Cancer of this type is very sensitive to estrogen, and to suppress it, the level of estrogen is reduced, and drugs are taken that are incapable of conversion in case of certain injuries or diseases.

So, in the case of women, testosterone is used in breast cancer, since the androgens in the female body are not converted to estrogen, unlike the male

4. Estrogens. By the way, about estrogen – the female sex hormone, not anabolic, but for a woman it is important. As for men, testosterone, as I wrote above, is very important for the connective tissue – the joints. He, like testosterone, has a positive effect on bone tissue, strengthening it.

Note: estrogen is just as important in metabolic processes in the male body as it is in the female, it takes part in many physiological processes, and the health of the joints and ligaments also depends on them.

In short, almost all diseases originate when hormonal levels fall, and the body begins to fade, and problems with connective tissue, joints and bones begin.

Instead of the total

Androgenic steroids have side effects, it is quite natural. All drugs and substances have the flip side of the coin, the only question is what degree of complexity are side effects and how dangerous are they to health. Anabolic steroids have an effect (on the kidneys, liver, gastrointestinal tract, skin and reproductive function).

It is considered that AAS sterilizes male testicles, so my advice to you, comrades, is not to experiment, and during the course you should use contraceptives, in other words, condoms, and then your second half may be a surprise to you.

In general, the moral is – do not believe everything that they write all sorts of dubious guys. And for such characters that mislead people, situations arise – like (aerial).

Post course therapy

Speaking frankly, I didn’t really want to write on this topic. Why? First of all, because there is no single recipe for all AAC users – we are all different and the article is in any case not a direct guide to action, but only the author’s subjective view of the problem in the title. I was encouraged to write this opus, a proposal by the administration of one forum to write a small educational program on the subject of the PCT, focused mainly on beginners. So that they do not litter the forum with the same type of questions, irritating experienced “pharmacists”. “Why not?” – I thought, all some kind of benefit will be. But writing short and peremptory instructions, it seems to me in this case unproductive for the reasons stated above, the article will force a person to wiggle a little and choose the most acceptable option for themselves. Anyway, I hope so.

Why do you need it?

For a start, let’s see why this postcourse therapy is needed? Well, firstly (and this is obvious), the introduction of exogenous hormones leads to an imbalance in the body, the existence of which is not very comfortable. The body, of course, is to a certain extent a self-regulating system, but it would be nice to help it, without waiting for it to cope with the task. Secondly (and this doesn’t seem so obvious anymore), the PCT can help preserve the “earned by overwork” – that is, the muscle mass gained during the course. Well, in the event that, except for water retention, you managed to collect something. Why does this “second” thing not seem so obvious to me? To do this, we need to turn to the queen of sciences – mathematics. Suppose your course consisted of 500 mg of testosterone enanthate per week (I do not consider smaller numbers, because I believe that only a very small number of people can count on a serious return from, say, 250 mg of testosterone enanthate per week). So, we have 500 mg of testosterone enanthate per week. Enanthate ether weighs about 150 mg of these 500, that is, 350 mg remains of pure testosterone. If we take the half-life of enanthate in a week, we get 175 mg of testosterone. Remember the number? Now let’s calculate how much testosterone a week is “worked out” by the average man. The normal daily secretion range is from 4 to 9 mg. We take the upper indicator (although nowadays poor ecology and unimportant general health of the population are clearly not the most common indicator), multiply by 7 (the number of days per week) and we get 63 mg. Well, what do you think, dear readers, will you be able to keep the typed amount of 175 for 63 mg? The question, in my opinion, is rhetorical … Of course, such a calculation is not very correct, but it reflects the big picture quite accurately. However, 63 mg is definitely more than nothing …

When and where to start?

As you know, the best treatment is prevention, so you need to start with it. For this I can offer two solutions that seem to me quite logical and reasonable: firstly, any course containing drugs with progestogenic activity, accompanied by parallel administration of drugs based on cabergoline (dostinex, agalates, bergolak). This will definitely protect against unwanted side effects associated with prolactin and facilitate recovery from the course. It is enough to take half a tablet 2 times a week. And secondly – if you use drugs that significantly reduce the level of endogenous testosterone (I will not give the list – it will be very long), do every second week of the course 2 injections of gonadotropin, 500 IU each. This will help to avoid dystrophy of the testicles, and the recovery of testosterone after the course will be more fun. I would especially recommend it to those athletes who have plans to continue the race – although there are no confirmed cases of sterility from AAS, restoring normal spermatogenesis after several years of using steroids is a difficult task for many people and takes a lot of time – for example, it took the author it’s about six months in this situation. And this is still a good result. Well, let us turn finally to the FCT itself – how much one can walk “around and about”. I do not know about you, readers, but it seems to me that recovery will begin only when the number of exogenous steroids in the body is small enough. There are two options here – if your course was built solely on “long-playing” broadcasts, you will have to wait a period of time – say, two weeks, after which it makes sense to start a PCT. The option is definitely not the most successful – during these two weeks, the level of catabolic hormones will increase rapidly. Therefore, it is more logical to finish the course on preparations with short esters, then after a couple of days you can begin the recovery. Ideally, if you don’t want to move by touch, so to speak, it’s better to pass some tests and to carry out appropriate recovery measures based on them.

Here is a list of them:

  • Lg;
  • FSH;
  • estradiol;
  • prolactin;
  • cortisol.

But, unfortunately, our whole life is far from ideal and to someone the same analyzes can simply be not available for one reason or another. In this case, you do not need to be a clairvoyant or hereditary magician to claim that after the course of LH and FSH, you will be lowered, and the rest of the indicators from the list are higher than the established reference values. Our task is to achieve their normalization. In fact, this task can be divided into two: restoration of normal testosterone levels and cortisol reduction. Restoration of normal testosterone levels. The task, in fact, is not so trivial enough often – as you know, testosterone secretion is controlled by the HH axis – hypothalamus – pituitary – testicles and suppression can occur at all levels. In the most favorable case, when suppression at the level of the hypothalamus is not pronounced, it is enough to lower the level of estrogen and testosterone secretion, which is regulated by feedback, will increase. Here, either anti-estrogens are applicable, or their combination with aromatase inhibitors. As for specific recommendations, if they are antiestrogens, then either tamoxifen, 20-40 mg per day, or Clomid, 100-150 mg per day. In addition to blocking the action of estradiol, antiestrogens promote the secretion of LH by the pituitary gland. Adding IA to them is usually not so necessary, but if the level of estrogen goes off scale, they will not be superfluous here. Of the aromatase inhibitors, exemestane (aromazine) is preferable – it has fewer side effects compared to “classmates” and its activity does not decrease when used together with antiestrogens. The only point that I would like to draw attention to is that if arimidex or letrozole was used on the course, aromazine for some unknown reason does not work after them. If you have taken cabergoline throughout the course with progestogens, you should have no problems with prolactin. Although in a small percentage of men, even the administration of exogenous testosterone can lead to an increase in prolactin. It will help all the same cabergoline.

Avoiding hormonal “pits” and not falling in the eyes of the beautiful half of humanity during recovery can help Proviron, although with prolonged use it can reduce testosterone, since it is in fact an oral form of dihydrotestosterone. He can also reduce the level of SHBG. The use of gonadotropin after the course can be justified with long courses with significant dosages of strong androgens – in such cases, the suppression of testosterone deep and tropic regulation based on the feedback principle may not work. That is, a decrease in estrogen alone will not lead to an increase in testosterone. In this case, it is worth resorting to injection of gonadotropin 1000 IU every other day for 10-14 days at the very beginning of the PCT. This is with regard to pharmaceutical preparations, but preparations from the arsenal of sports nutrition can also help us. Tribulus, which for a long time was almost an obligatory attribute of PCT, according to the results of all modern studies, does not affect the level of PH, but can only increase the level of DHT, which proiron is much better able to handle. He was replaced by D-aspartic acid (especially its methylated version) as a headliner. According to research results, D-aspartic acid, when taken in an amount of 3 grams per day, increased testosterone levels by 42% in 12 days of intake. This, or slightly larger dosage, and should be taken on the PCT. Vitamin and mineral complexes will help us in our difficult work. But it’s worth mentioning one mineral – zinc regulates the amount of androgen receptors in the body, with its deficiency the level of testosterone drops. It is better to take it as part of an additive called ZMA – the combination of zinc with magnesium and vitamin B6 allows it to be better absorbed.